6.5M XNYS Volume
XNYS 28 Mar, 2025 5:30 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 212.34 per share. | 14 Mar 2025 | 17,644 | 11,577 (0%) | 0% | 212.3 | 3,746,527 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director | Payment of exercise price or tax liability using portion of securities received from the company at price $ 205.02 per share. | 28 Feb 2025 | 73,209 | 487,557 (0%) | 0% | 205.0 | 15,009,309 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director | Sale of securities on an exchange or to another person at price $ 205.11 per share. | 28 Feb 2025 | 92,460 | 395,097 (0%) | 0% | 205.1 | 18,964,471 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director | Sale of securities on an exchange or to another person at price $ 210.53 per share. | 28 Feb 2025 | 6,168 | 388,929 (0%) | 0% | 210.5 | 1,298,549 | Common Stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 205.02 per share. | 28 Feb 2025 | 16,904 | 27,380 (0%) | 0% | 205.0 | 3,465,658 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 209.80 per share. | 28 Feb 2025 | 5,677 | 21,703 (0%) | 0% | 209.8 | 1,191,035 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 210.66 per share. | 28 Feb 2025 | 14,973 | 6,730 (0%) | 0% | 210.7 | 3,154,212 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 211.32 per share. | 28 Feb 2025 | 600 | 6,130 (0%) | 0% | 211.3 | 126,792 | Common stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, CHIEF OPERATIONS OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 205.02 per share. | 28 Feb 2025 | 17,056 | 177,292 (0%) | 0% | 205.0 | 3,496,821 | Common Stock, $0.01 par value |
| Robert A. Michael | Director, CHIEF EXECUTIVE OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 205.02 per share. | 28 Feb 2025 | 27,186 | 132,821 (0%) | 0% | 205.0 | 5,573,674 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 205.02 per share. | 28 Feb 2025 | 20,226 | 86,366 (0%) | 0% | 205.0 | 4,146,735 | Common Stock, $0.01 par value |
| Nicholas J. Donoghoe | EVP, CHIEF BUS/STRAT OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 205.02 per share. | 28 Feb 2025 | 11,230 | 70,018 (0%) | 0% | 205.0 | 2,302,375 | Common Stock, $0.01 par value |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 205.02 per share. | 28 Feb 2025 | 10,973 | 29,221 (0%) | 0% | 205.0 | 2,249,684 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale or transfer of securities back to the company at price $ 0.00 per share. | 28 Feb 2025 | 7,315 | 7,314 | - | - | Option (Right to buy) | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 206.62 per share. | 28 Feb 2025 | 6,811 | 4,982 (0%) | 0% | 206.6 | 1,407,289 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 207.19 per share. | 28 Feb 2025 | 363 | 4,619 (0%) | 0% | 207.2 | 75,210 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Payment of exercise price or tax liability using portion of securities received from the company at price $ 205.02 per share. | 28 Feb 2025 | 7,870 | 14,511 (0%) | 0% | 205.0 | 1,613,507 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 205.38 per share. | 28 Feb 2025 | 2,718 | 11,793 (0%) | 0% | 205.4 | 558,223 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale or transfer of securities back to the company at price $ 0.00 per share. | 28 Feb 2025 | 7,775 | 15,549 | - | - | Option (Right to buy) | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 144.54 per share. | 28 Feb 2025 | 2,918 | 7,537 (0%) | 0% | 144.5 | 421,768 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale or transfer of securities back to the company at price $ 0.00 per share. | 28 Feb 2025 | 2,918 | 0 | - | - | Option (Right to buy) | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 210.00 per share. | 28 Feb 2025 | 18,008 | 4,619 (0%) | 0% | 210 | 3,781,680 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 175.28 per share. | 28 Feb 2025 | 7,775 | 22,627 (0%) | 0% | 175.3 | 1,362,802 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 149.62 per share. | 28 Feb 2025 | 7,315 | 14,852 (0%) | 0% | 149.6 | 1,094,470 | Common Stock, $0.01 par value |
| Kevin K. Buckbee | SVP, CONTROLLER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 205.02 per share. | 28 Feb 2025 | 3,699 | 7,797 (0%) | 0% | 205.0 | 758,369 | Common Stock, $0.01 par value |
| Roopal Thakkar | EVP, R&D and CSO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 205.02 per share. | 28 Feb 2025 | 4,678 | 42,276 (0%) | 0% | 205.0 | 959,084 | Common Stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 22,210 | 0 | - | - | Option (Right to buy) | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 202.06 per share. | 26 Feb 2025 | 1,400 | 50,591 (0%) | 0% | 202.1 | 282,884 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 202.93 per share. | 26 Feb 2025 | 4,781 | 45,810 (0%) | 0% | 202.9 | 970,208 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 203.64 per share. | 26 Feb 2025 | 1,526 | 44,284 (0%) | 0% | 203.6 | 310,755 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 114.36 per share. | 26 Feb 2025 | 22,210 | 66,494 (0%) | 0% | 114.4 | 2,539,936 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 201.97 per share. | 26 Feb 2025 | 4,308 | 62,186 (0%) | 0% | 202.0 | 870,087 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 202.92 per share. | 26 Feb 2025 | 13,073 | 49,113 (0%) | 0% | 202.9 | 2,652,773 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 203.63 per share. | 26 Feb 2025 | 4,829 | 44,284 (0%) | 0% | 203.6 | 983,329 | Common stock, $0.01 par value |
| Kevin K. Buckbee | SVP, CONTROLLER | Sale of securities on an exchange or to another person at price $ 203.40 per share. | 26 Feb 2025 | 2,684 | 12,646 (0%) | 0% | 203.4 | 545,926 | Common Stock, $0.01 par value |
| Kevin K. Buckbee | SVP, CONTROLLER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 6,522 | 2,794 | - | - | Option (Right to buy) | |
| Kevin K. Buckbee | SVP, CONTROLLER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 26 Feb 2025 | 9,738 | 2,373 | - | - | Option (Right to buy) | |
| Kevin K. Buckbee | SVP, CONTROLLER | Sale of securities on an exchange or to another person at price $ 203.41 per share. | 26 Feb 2025 | 16,260 | 11,496 (0%) | 0% | 203.4 | 3,307,447 | Common Stock, $0.01 par value |
| Kevin K. Buckbee | SVP, CONTROLLER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 105.92 per share. | 26 Feb 2025 | 6,522 | 28,906 (0%) | 0% | 105.9 | 690,810 | Common Stock, $0.01 par value |
| Kevin K. Buckbee | SVP, CONTROLLER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 93.50 per share. | 26 Feb 2025 | 9,738 | 22,384 (0%) | 0% | 93.5 | 910,503 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 197.40 per share. | 20 Feb 2025 | 1,784 | 26,375 (0%) | 0% | 197.4 | 352,162 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 198.12 per share. | 20 Feb 2025 | 3,994 | 22,381 (0%) | 0% | 198.1 | 791,291 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 80,945 | 469,874 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 33,208 | 503,082 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 30,298 | 533,380 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 27,386 | 560,766 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 65,104 | 65,104 | - | - | Option (Right to Buy) | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 7,378 | 39,201 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 22,916 | 22,916 | - | - | Option (Right to buy) | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 6,998 | 51,991 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 5,792 | 44,993 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 17,986 | 31,823 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| Azita Saleki-Gerhardt | EVP, CHIEF OPERATIONS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 25,000 | 25,000 | - | - | Option (Right to Buy) | |
| Azita Saleki-Gerhardt | EVP, CHIEF OPERATIONS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 17,986 | 212,334 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Azita Saleki-Gerhardt | EVP, CHIEF OPERATIONS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 7,378 | 219,712 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Azita Saleki-Gerhardt | EVP, CHIEF OPERATIONS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 6,060 | 225,772 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Azita Saleki-Gerhardt | EVP, CHIEF OPERATIONS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 7,074 | 232,846 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert A. Michael | Director, CHIEF EXECUTIVE OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 24,732 | 123,377 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert A. Michael | Director, CHIEF EXECUTIVE OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 10,146 | 133,523 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert A. Michael | Director, CHIEF EXECUTIVE OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 12,030 | 145,553 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert A. Michael | Director, CHIEF EXECUTIVE OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 14,454 | 160,007 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert A. Michael | Director, CHIEF EXECUTIVE OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 83,333 | 83,333 | - | - | Option (Right to Buy) | |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 7,840 | 87,892 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 19,111 | 80,052 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 33,854 | 33,854 | - | - | Option (Right to Buy) | |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 9,432 | 106,592 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 9,268 | 97,160 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Nicholas Donoghoe J. | EVP, CHIEF BUS/STRAT OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 23,437 | 23,437 | - | - | Option (Right to buy) | |
| Nicholas Donoghoe J. | EVP, CHIEF BUS/STRAT OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 11,017 | 66,920 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Nicholas Donoghoe J. | EVP, CHIEF BUS/STRAT OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 4,520 | 71,440 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Nicholas Donoghoe J. | EVP, CHIEF BUS/STRAT OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 4,634 | 76,074 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Nicholas Donoghoe J. | EVP, CHIEF BUS/STRAT OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 5,174 | 81,248 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 2,398 | 23,674 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 8,912 | 32,586 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 7,608 | 40,194 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 27,343 | 27,343 | - | - | Option (Right to buy) | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 5,845 | 21,276 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 1,844 | 16,737 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 5,792 | 22,529 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 5,630 | 28,159 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 21,875 | 21,875 | - | - | Option (Right to buy) | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 4,496 | 14,893 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Kevin K. Buckbee | SVP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 3,595 | 10,578 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Kevin K. Buckbee | SVP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 6,250 | 6,250 | - | - | Option (Right to buy) | |
| Kevin K. Buckbee | SVP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 1,674 | 15,330 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Kevin K. Buckbee | SVP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 1,604 | 13,656 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Kevin K. Buckbee | SVP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 1,474 | 12,052 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roopal Thakkar | EVP, R&D and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 1,474 | 41,468 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roopal Thakkar | EVP, R&D and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 25,000 | 25,000 | - | - | Option (Right to buy) | |
| Roopal Thakkar | EVP, R&D and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 3,348 | 46,954 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roopal Thakkar | EVP, R&D and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 2,138 | 43,606 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roopal Thakkar | EVP, R&D and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2025 | 3,595 | 39,994 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2024 | 42 | 9,788 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2024 | 182 | 26,976 | - | - | Stock Equivalent Units | |
| Susan E. Quaggin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2024 | 84 | 401 | - | - | Stock Equivalent Units | |
| K. Buckbee Kevin | SVP, CONTROLLER | Sale of securities on an exchange or to another person at price $ 172.24 per share. | 16 Dec 2024 | 1,800 | 6,983 (0%) | 0% | 172.2 | 310,032 | Common Stock, $0.01 par value |
| Buckbee K. Kevin | SVP, CONTROLLER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Dec 2024 | 1,800 | 12,111 | - | - | Option (Right to buy) | |
| K. Buckbee Kevin | SVP, CONTROLLER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 93.50 per share. | 16 Dec 2024 | 1,800 | 8,783 (0%) | 0% | 93.5 | 168,300 | Common Stock, $0.01 par value |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2024 | 37 | 9,655 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2024 | 164 | 26,544 | - | - | Stock Equivalent Units | |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Sep 2024 | 5,243 | 441,356 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Sep 2024 | 36,698 | 388,929 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Gift of securities by or to the insider at price $ 0.00 per share. | 30 Sep 2024 | 15,729 | 425,627 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Susan E. Quaggin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2024 | 75 | 314 | - | - | Stock Equivalent Units | |
| Azita Saleki-Gerhardt | EVP, CHIEF OPERATIONS OFFICER | Gift of securities by or to the insider at price $ 0.00 per share. | 24 Sep 2024 | 25,630 | 194,348 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Sale of securities on an exchange or to another person at price $ 186.52 per share. | 05 Aug 2024 | 66,500 | 446,599 (0%) | 0% | 186.5 | 12,403,580 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Exercise or conversion of derivative security received from the company (such as an option) at price $ 61.36 per share. | 17 Jul 2024 | 87,050 | 600,149 (0%) | 0% | 61.4 | 5,341,388 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jul 2024 | 76,377 | 152,755 | - | - | Option (Right To Buy) | |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jul 2024 | 119,418 | 59,709 | - | - | Option (Right To Buy) | |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 17 Jul 2024 | 87,050 | 0 | - | - | Option (Right To Buy) | |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Sale of securities on an exchange or to another person at price $ 175.00 per share. | 17 Jul 2024 | 282,845 | 513,099 (0%) | 0% | 175 | 49,497,875 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Exercise or conversion of derivative security received from the company (such as an option) at price $ 93.50 per share. | 17 Jul 2024 | 76,377 | 795,944 (0%) | 0% | 93.5 | 7,141,250 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director, EXECUTIVE CHAIRMAN OF BOARD | Exercise or conversion of derivative security received from the company (such as an option) at price $ 79.02 per share. | 17 Jul 2024 | 119,418 | 719,567 (0%) | 0% | 79.0 | 9,436,410 | Common Stock, $0.01 par value |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2024 | 43 | 9,541 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2024 | 225 | 26,170 | - | - | Stock Equivalent Units | |
| Susan E. Quaggin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2024 | 87 | 236 | - | - | Stock Equivalent Units | |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 28 Jun 2024 | 6,000 | 513,099 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Frederick H. Waddell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 27,755 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Glenn F. Tilton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 50,361 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Rebecca B. Roberts | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 12,525 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 34,443 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Thomas C. Freyman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 125,548 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 31,356 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roxanne S. Austin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 37,255 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Brett J. Hart | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 18,269 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| William H.L. Burnside | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 25,755 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Melody B. Meyer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 15,295 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Jennifer L. Davis | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 1,322 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Susan E. Quaggin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 03 May 2024 | 1,322 | 1,322 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2024 | 41 | 9,408 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2024 | 212 | 25,701 | - | - | Stock Equivalent Units | |
| Susan E. Quaggin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2024 | 82 | 147 | - | - | Stock Equivalent Units | |
| Nicholas Donoghoe | EVP, CHIEF BUS/STRAT OFFICER | Sale of securities on an exchange or to another person at price $ 176.30 per share. | 20 Mar 2024 | 21,082 | 55,903 (0%) | 0% | 176.3 | 3,716,757 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 61.36 per share. | 18 Mar 2024 | 26,110 | 119,890 (0%) | 0% | 61.4 | 1,602,110 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 178.69 per share. | 18 Mar 2024 | 27,740 | 60,941 (0%) | 0% | 178.7 | 4,956,861 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 18 Mar 2024 | 26,110 | 0 | - | - | Option (Right to Buy) | |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 179.03 per share. | 18 Mar 2024 | 5,099 | 88,681 (0%) | 0% | 179.0 | 912,874 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 178.85 per share. | 18 Mar 2024 | 26,110 | 93,780 (0%) | 0% | 178.9 | 4,669,774 | Common Stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 61.36 per share. | 01 Mar 2024 | 45,700 | 89,517 (0%) | 0% | 61.4 | 2,804,152 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 01 Mar 2024 | 45,700 | 0 | - | - | Option (Right to buy) | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 177.71 per share. | 01 Mar 2024 | 20,127 | 13,837 (0%) | 0% | 177.7 | 3,576,769 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 177.71 per share. | 01 Mar 2024 | 30,288 | 43,817 (0%) | 0% | 177.7 | 5,382,480 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 176.40 per share. | 01 Mar 2024 | 15,412 | 74,105 (0%) | 0% | 176.4 | 2,718,677 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 176.35 per share. | 01 Mar 2024 | 9,853 | 33,964 (0%) | 0% | 176.4 | 1,737,577 | Common stock, $0.01 par value |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 178.99 per share. | 28 Feb 2024 | 110,249 | 657,715 (0%) | 0% | 179.0 | 19,733,469 | Common Stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 178.99 per share. | 28 Feb 2024 | 23,847 | 43,817 (0%) | 0% | 179.0 | 4,268,375 | Common stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, CHIEF OPERATIONS OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 178.99 per share. | 28 Feb 2024 | 23,966 | 219,978 (0%) | 0% | 179.0 | 4,289,674 | Common Stock, $0.01 par value |
| Robert A. Michael | PRES & CHIEF OPERATING OFFICER | Sale of securities on an exchange or to another person at price $ 176.44 per share. | 28 Feb 2024 | 21,560 | 145,964 (0%) | 0% | 176.4 | 3,804,046 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Sale of securities on an exchange or to another person at price $ 177.27 per share. | 28 Feb 2024 | 138,616 | 519,099 (0%) | 0% | 177.3 | 24,572,458 | Common Stock, $0.01 par value |
| Robert A. Michael | PRES & CHIEF OPERATING OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2024 | 11,420 | 0 | - | - | Option (Right to Buy) | |
| Robert A. Michael | PRES & CHIEF OPERATING OFFICER | Sale of securities on an exchange or to another person at price $ 176.46 per share. | 28 Feb 2024 | 47,319 | 98,645 (0%) | 0% | 176.5 | 8,349,911 | Common Stock, $0.01 par value |
| Robert A. Michael | PRES & CHIEF OPERATING OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2024 | 10,140 | 0 | - | - | Option (Right to Buy) | |
| Robert A. Michael | PRES & CHIEF OPERATING OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 54.86 per share. | 28 Feb 2024 | 10,140 | 167,524 (0%) | 0% | 54.9 | 556,280 | Common Stock, $0.01 par value |
| Robert A. Michael | PRES & CHIEF OPERATING OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 61.36 per share. | 28 Feb 2024 | 11,420 | 157,384 (0%) | 0% | 61.4 | 700,731 | Common Stock, $0.01 par value |
| Robert A. Michael | PRES & CHIEF OPERATING OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 178.99 per share. | 28 Feb 2024 | 37,638 | 145,964 (0%) | 0% | 179.0 | 6,736,826 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 178.99 per share. | 28 Feb 2024 | 26,121 | 93,780 (0%) | 0% | 179.0 | 4,675,398 | Common Stock, $0.01 par value |
| Nicholas Donoghoe | EVP, CHIEF BUS/STRAT OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 178.99 per share. | 28 Feb 2024 | 16,771 | 76,985 (0%) | 0% | 179.0 | 3,001,841 | Common Stock, $0.01 par value |
| Thomas J. Hudson | SVP, CSO, GLOBAL RESEARCH | 28 Feb 2024 | 20,634 | 107,267 (0%) | 0% | 179.0 | 3,693,280 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 177.05 per share. | 28 Feb 2024 | 6,504 | 13,784 (0%) | 0% | 177.0 | 1,151,533 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Payment of exercise price or tax liability using portion of securities received from the company at price $ 178.99 per share. | 28 Feb 2024 | 7,885 | 20,288 (0%) | 0% | 179.0 | 1,411,336 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 178.04 per share. | 28 Feb 2024 | 3,387 | 10,397 (0%) | 0% | 178.0 | 603,021 | Common Stock, $0.01 par value |
| Kevin K. Buckbee | SVP, CONTROLLER | Sale of securities on an exchange or to another person at price $ 176.65 per share. | 28 Feb 2024 | 5,144 | 6,983 (0%) | 0% | 176.7 | 908,688 | Common Stock, $0.01 par value |
| Kevin K. Buckbee | SVP, CONTROLLER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 178.99 per share. | 28 Feb 2024 | 5,339 | 13,872 (0%) | 0% | 179.0 | 955,628 | Common Stock, $0.01 par value |
| Roopal Thakkar | SVP, CMO, GLOBAL THERAPEUTICS | Payment of exercise price or tax liability using portion of securities received from the company at price $ 178.99 per share. | 28 Feb 2024 | 4,914 | 23,259 (0%) | 0% | 179.0 | 879,557 | Common Stock, $0.01 par value |
| Richard Gonzalez A. | Director, CHAIRMAN OF THE BOARD AND CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Feb 2024 | 2,525 | 767,964 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| A. Richard Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 27 Feb 2024 | 1,670 | 770,489 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| C. Siatis Perry | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Feb 2024 | 7,315 | 14,629 | - | - | Option (Right to buy) | |
| Siatis Perry C. | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 144.54 per share. | 23 Feb 2024 | 2,919 | 31,092 (0%) | 0% | 144.5 | 421,912 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 105.92 per share. | 23 Feb 2024 | 3,519 | 34,611 (0%) | 0% | 105.9 | 372,732 | Common Stock, $0.01 par value |
| Perry Siatis C. | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Feb 2024 | 2,919 | 2,919 | - | - | Option (Right to buy) | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 149.62 per share. | 23 Feb 2024 | 7,315 | 41,926 (0%) | 0% | 149.6 | 1,094,470 | Common Stock, $0.01 par value |
| Siatis Perry C. | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 177.51 per share. | 23 Feb 2024 | 13,753 | 28,173 (0%) | 0% | 177.5 | 2,441,295 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Feb 2024 | 3,519 | 0 | - | - | Option (Right to buy) | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 Feb 2024 | 14,140 | 17,380 | - | - | Option (Right to buy) | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 178.99 per share. | 23 Feb 2024 | 11,634 | 15,431 (0%) | 0% | 179.0 | 2,082,370 | Common Stock, $0.01 par value |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 177.44 per share. | 23 Feb 2024 | 14,140 | 27,065 (0%) | 0% | 177.4 | 2,509,002 | Common Stock, $0.01 par value |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 61.36 per share. | 23 Feb 2024 | 14,140 | 41,205 (0%) | 0% | 61.4 | 867,630 | Common Stock, $0.01 par value |
| Saleki-Gerhardt Azita | EVP, CHIEF OPERATIONS OFFICER | Sale of securities on an exchange or to another person at price $ 173.71 per share. | 21 Feb 2024 | 52,870 | 243,944 (0%) | 0% | 173.7 | 9,184,048 | Common Stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, CHIEF OPERATIONS OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.88 per share. | 21 Feb 2024 | 52,870 | 296,814 (0%) | 0% | 58.9 | 3,112,986 | Common Stock, $0.01 par value |
| Saleki-Gerhardt Azita | EVP, CHIEF OPERATIONS OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Feb 2024 | 52,870 | 0 | - | - | Option (Right to Buy) | |
| Roopal Thakkar | SVP, CMO, GLOBAL THERAPEUTICS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 5,792 | 28,173 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 8,912 | 27,065 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 33,042 | 93,983 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Hudson J. Thomas | SVP, CSO, GLOBAL RESEARCH | 15 Feb 2024 | 5,350 | 122,553 (0%) | 0% | 0 | Common Stock, $0.01 par value | ||
| K. Kevin Buckbee | SVP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 6,934 | 6,934 | - | - | Option (Right to buy) | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 11,800 | 12,609 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Reents Scott | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 31,520 | 31,520 | - | - | Option (Right to buy) | |
| Perry Siatis C. | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 5,792 | 28,173 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| J. Thomas Hudson | SVP, CSO, GLOBAL RESEARCH | 15 Feb 2024 | 5,348 | 127,901 (0%) | 0% | 0 | Common Stock, $0.01 par value | ||
| Saleki-Gerhardt Azita | EVP, CHIEF OPERATIONS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 29,313 | 29,313 | - | - | Option (Right to Buy) | |
| Nicholas Donoghoe | EVP, CHIEF BUS/STRAT OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 4,520 | 89,122 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 3,146 | 15,755 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Nicholas Donoghoe | EVP, CHIEF BUS/STRAT OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 22,657 | 78,560 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Reents Scott | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 2,398 | 18,153 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| K. Buckbee Kevin | SVP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 1,476 | 17,607 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry Siatis C. | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 2,138 | 20,537 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 1,844 | 22,381 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 7,380 | 61,872 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| A. Robert Michael | PRES & CHIEF OPERATING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 59,888 | 59,888 | - | - | Option (Right to Buy) | |
| A. Robert Michael | PRES & CHIEF OPERATING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 10,146 | 171,572 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Saleki-Gerhardt Azita | EVP, CHIEF OPERATIONS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 7,380 | 237,884 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| K. Kevin Buckbee | SVP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 7,080 | 14,243 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Stewart Ryan Jeffrey | EVP, CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 7,840 | 110,633 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Azita Saleki-Gerhardt | EVP, CHIEF OPERATIONS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 6,060 | 243,944 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| A. Richard Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 113,472 | 113,472 | - | - | Option (Right to Buy) | |
| Thakkar Roopal | SVP, CMO, GLOBAL THERAPEUTICS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 1,844 | 22,381 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Stewart Ryan Jeffrey | EVP, CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 9,268 | 119,901 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Ryan Stewart Jeffrey | EVP, CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 39,085 | 39,085 | - | - | Option (Right to Buy) | |
| Kevin Buckbee K. | SVP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 1,604 | 19,211 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Buckbee K. Kevin | SVP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 1,888 | 16,131 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Siatis C. Perry | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 23,324 | 23,324 | - | - | Option (Right to buy) | |
| Saleki-Gerhardt Azita | EVP, CHIEF OPERATIONS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 8,558 | 230,504 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| A. Robert Michael | PRES & CHIEF OPERATING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 12,030 | 183,602 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Nicholas Donoghoe | EVP, CHIEF BUS/STRAT OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 4,634 | 93,756 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| J. Thomas Hudson | SVP, CSO, GLOBAL RESEARCH | 15 Feb 2024 | 18,912 | 18,912 | - | - | Option (Right to Buy) | ||
| Thakkar Roopal | SVP, CMO, GLOBAL THERAPEUTICS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 2,138 | 20,537 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Thomas J. Hudson | SVP, CSO, GLOBAL RESEARCH | 15 Feb 2024 | 7,552 | 117,203 (0%) | 0% | 0 | Common Stock, $0.01 par value | ||
| Saleki-Gerhardt Azita | EVP, CHIEF OPERATIONS OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 32,097 | 221,946 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richmond Timothy J. | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 8,558 | 54,492 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| Michael Robert A. | PRES & CHIEF OPERATING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 13,216 | 161,426 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 146,335 | 669,629 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Thakkar Roopal | SVP, CMO, GLOBAL THERAPEUTICS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 13,868 | 13,868 | - | - | Option (Right to buy) | |
| Thakkar Roopal | SVP, CMO, GLOBAL THERAPEUTICS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 8,022 | 18,399 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Timothy Richmond J. | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 5,792 | 67,664 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| A. Richard Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 33,208 | 741,859 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Nicholas Donoghoe | EVP, CHIEF BUS/STRAT OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 21,433 | 21,433 | - | - | Option (Right to buy) | |
| Richmond J. Timothy | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 28,998 | 28,998 | - | - | Option (Right to buy) | |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 8,810 | 102,793 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Gonzalez A. Richard | Director, CHAIRMAN OF THE BOARD AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 39,022 | 708,651 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 32,097 | 45,934 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| Thomas J. Hudson | SVP, CSO, GLOBAL RESEARCH | 15 Feb 2024 | 28,322 | 109,651 (0%) | 0% | 0 | Common Stock, $0.01 par value | ||
| Donoghoe Nicholas | EVP, CHIEF BUS/STRAT OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 6,042 | 84,602 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Michael A. Robert | PRES & CHIEF OPERATING OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 49,565 | 148,210 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Siatis C. Perry | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 8,022 | 18,399 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 30,300 | 772,159 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roopal Thakkar | EVP, R&D and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 2,140 | 41,313 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roopal Thakkar | EVP, R&D and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 13,868 | 13,868 | - | - | Option (Right to buy) | |
| Roopal Thakkar | EVP, R&D and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 1,572 | 37,697 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roopal Thakkar | EVP, R&D and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 1,476 | 39,173 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roopal Thakkar | EVP, R&D and CSO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2024 | 5,900 | 36,125 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| C. Perry Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 144.54 per share. | 02 Feb 2024 | 2,919 | 13,296 (0%) | 0% | 144.5 | 421,912 | Common Stock, $0.01 par value |
| C. Siatis Perry | EVP, GC AND SECRETARY | Sale or transfer of securities back to the company at price $ 170.00 per share. | 02 Feb 2024 | 2,919 | 10,377 (0%) | 0% | 170 | 496,230 | Common Stock, $0.01 par value |
| Siatis Perry C. | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 02 Feb 2024 | 2,919 | 5,837 | - | - | Option (Right to buy) | |
| Robert Alpern J. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2023 | 48 | 9,285 | - | - | Stock Equivalent Units | |
| Edward Rapp J. | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2023 | 250 | 25,266 | - | - | Stock Equivalent Units | |
| Quaggin Susan | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2023 | 64 | 64 | - | - | Stock Equivalent Units | |
| Donoghoe Nicholas | EVP, CHIEF BUS/STRAT OFFICER | Sale of securities on an exchange or to another person at price $ 154.72 per share. | 26 Dec 2023 | 2,912 | 55,903 (0%) | 0% | 154.7 | 450,545 | Common Stock, $0.01 par value |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2023 | 50 | 9,139 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2023 | 259 | 24,750 | - | - | Stock Equivalent Units | |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 25 Sep 2023 | 42,000 | 523,294 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert J. Alpern | Director | 07 Sep 2023 | 129 | 33,121 (0%) | 0% | 0 | Common Stock, $0.01 par value | ||
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Sale of securities on an exchange or to another person at price $ 148.58 per share. | 31 Jul 2023 | 60,000 | 565,294 (0%) | 0% | 148.6 | 8,914,800 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Sale of securities on an exchange or to another person at price $ 149.15 per share. | 31 Jul 2023 | 18,500 | 625,294 (0%) | 0% | 149.2 | 2,759,275 | Common Stock, $0.01 par value |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 55 | 9,001 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2023 | 287 | 24,254 | - | - | Stock Equivalent Units | |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Payment of exercise price or tax liability using portion of securities received from the company at price $ 146.42 per share. | 11 May 2023 | 2,876 | 28,024 (0%) | 0% | 146.4 | 421,104 | Common Stock, $0.01 par value |
| Frederick H. Waddell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2023 | 1,450 | 26,433 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Glenn F. Tilton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2023 | 1,450 | 49,039 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Rebecca B. Roberts | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2023 | 1,450 | 11,203 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2023 | 1,450 | 32,992 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Thomas C. Freyman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2023 | 1,450 | 124,226 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2023 | 1,450 | 30,034 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roxanne S. Austin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2023 | 1,450 | 35,933 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Brett J. Hart | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2023 | 1,450 | 16,947 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| William H.L. Burnside | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2023 | 1,450 | 24,433 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Melody B. Meyer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 May 2023 | 1,450 | 13,973 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Glenn F. Tilton | Director | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Apr 2023 | 2,230 | 34,700 | - | - | Stock Equivalent Units | |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Sale of securities on an exchange or to another person at price $ 165.00 per share. | 25 Apr 2023 | 6,130 | 35,330 (0%) | 0% | 165 | 1,011,450 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Apr 2023 | 6,130 | 12,258 | - | - | Option (Right to Buy) | |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 144.54 per share. | 25 Apr 2023 | 6,130 | 41,460 (0%) | 0% | 144.5 | 886,030 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Sale of securities on an exchange or to another person at price $ 162.04 per share. | 17 Apr 2023 | 500 | 35,330 (0%) | 0% | 162.0 | 81,020 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Sale of securities on an exchange or to another person at price $ 161.64 per share. | 17 Apr 2023 | 6,999 | 35,830 (0%) | 0% | 161.6 | 1,131,318 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Sale of securities on an exchange or to another person at price $ 160.03 per share. | 03 Apr 2023 | 15,002 | 42,829 (0%) | 0% | 160.0 | 2,400,770 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Apr 2023 | 15,002 | 0 | - | - | Option (Right to Buy) | |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 93.50 per share. | 03 Apr 2023 | 15,002 | 57,831 (0%) | 0% | 93.5 | 1,402,687 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 03 Apr 2023 | 3,520 | 3,520 | - | - | Option (Right to buy) | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 160.00 per share. | 03 Apr 2023 | 3,520 | 10,377 (0%) | 0% | 160 | 563,200 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 105.92 per share. | 03 Apr 2023 | 3,520 | 13,897 (0%) | 0% | 105.9 | 372,838 | Common Stock, $0.01 par value |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2023 | 47 | 8,856 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2023 | 243 | 23,727 | - | - | Stock Equivalent Units | |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 152.30 per share. | 13 Mar 2023 | 21,810 | 92,256 (0%) | 0% | 152.3 | 3,321,663 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 13 Mar 2023 | 21,810 | 0 | - | - | Option (Right to Buy) | |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 152.27 per share. | 13 Mar 2023 | 31,315 | 60,941 (0%) | 0% | 152.3 | 4,768,335 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, CHIEF COMMERCIAL OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 54.86 per share. | 13 Mar 2023 | 21,810 | 114,066 (0%) | 0% | 54.9 | 1,196,497 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Payment of exercise price or tax liability using portion of securities received from the company at price $ 156.06 per share. | 05 Mar 2023 | 449 | 30,900 (0%) | 0% | 156.1 | 70,071 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 03 Mar 2023 | 2,550 | 643,794 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.28 per share. | 28 Feb 2023 | 113,810 | 646,344 (0%) | 0% | 154.3 | 17,558,607 | Common Stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 153.08 per share. | 28 Feb 2023 | 27,395 | 30,583 (0%) | 0% | 153.1 | 4,193,583 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 153.62 per share. | 28 Feb 2023 | 16,746 | 13,837 (0%) | 0% | 153.6 | 2,572,521 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.28 per share. | 28 Feb 2023 | 35,111 | 57,978 (0%) | 0% | 154.3 | 5,416,925 | Common stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.28 per share. | 28 Feb 2023 | 33,359 | 199,849 (0%) | 0% | 154.3 | 5,146,627 | Common Stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2023 | 26,990 | 0 | - | - | Option (Right to Buy) | |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Sale of securities on an exchange or to another person at price $ 153.39 per share. | 28 Feb 2023 | 780 | 189,849 (0%) | 0% | 153.4 | 119,644 | Common Stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Sale of securities on an exchange or to another person at price $ 153.05 per share. | 28 Feb 2023 | 9,220 | 190,629 (0%) | 0% | 153.1 | 1,411,121 | Common Stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Sale of securities on an exchange or to another person at price $ 155.00 per share. | 28 Feb 2023 | 26,990 | 199,849 (0%) | 0% | 155 | 4,183,450 | Common Stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 51.42 per share. | 28 Feb 2023 | 26,990 | 226,839 (0%) | 0% | 51.4 | 1,387,826 | Common Stock, $0.01 par value |
| Robert A. Michael | VICE CHAIRMAN | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.28 per share. | 28 Feb 2023 | 48,335 | 98,645 (0%) | 0% | 154.3 | 7,457,124 | Common Stock, $0.01 par value |
| Brian L. Durkin | VP, CONTROLLER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.28 per share. | 28 Feb 2023 | 11,182 | 33,149 (0%) | 0% | 154.3 | 1,725,159 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, COMMERCIAL OPERATIONS | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.28 per share. | 28 Feb 2023 | 24,910 | 92,256 (0%) | 0% | 154.3 | 3,843,115 | Common Stock, $0.01 par value |
| Thomas J. Hudson | SVP, R&D AND CSO | 28 Feb 2023 | 27,922 | 81,329 (0%) | 0% | 154.3 | 4,307,806 | Common Stock, $0.01 par value | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 153.38 per share. | 28 Feb 2023 | 850 | 809 (0%) | 0% | 153.4 | 130,373 | Common Stock, $0.01 par value |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Sale of securities on an exchange or to another person at price $ 153.06 per share. | 28 Feb 2023 | 15,092 | 1,659 (0%) | 0% | 153.1 | 2,309,982 | Common Stock, $0.01 par value |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.28 per share. | 28 Feb 2023 | 12,683 | 16,751 (0%) | 0% | 154.3 | 1,956,733 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Payment of exercise price or tax liability using portion of securities received from the company at price $ 155.27 per share. | 28 Feb 2023 | 810 | 31,349 (0%) | 0% | 155.3 | 125,769 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.28 per share. | 28 Feb 2023 | 5,762 | 32,159 (0%) | 0% | 154.3 | 888,961 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 93.50 per share. | 28 Feb 2023 | 15,003 | 57,832 (0%) | 0% | 93.5 | 1,402,781 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Sale of securities on an exchange or to another person at price $ 155.00 per share. | 28 Feb 2023 | 15,003 | 42,829 (0%) | 0% | 155 | 2,325,465 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 28 Feb 2023 | 15,003 | 0 | - | - | Option (Right to Buy) | |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.28 per share. | 28 Feb 2023 | 19,850 | 42,829 (0%) | 0% | 154.3 | 3,062,458 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Payment of exercise price or tax liability using portion of securities received from the company at price $ 154.28 per share. | 28 Feb 2023 | 9,656 | 22,512 (0%) | 0% | 154.3 | 1,489,728 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 153.38 per share. | 28 Feb 2023 | 805 | 10,377 (0%) | 0% | 153.4 | 123,471 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 153.06 per share. | 28 Feb 2023 | 11,330 | 11,182 (0%) | 0% | 153.1 | 1,734,170 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 21 Feb 2023 | 7,364 | 0 | - | - | Option (Right to buy) | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 151.29 per share. | 21 Feb 2023 | 3,933 | 32,168 (0%) | 0% | 151.3 | 595,024 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Sale of securities on an exchange or to another person at price $ 150.73 per share. | 21 Feb 2023 | 3,431 | 36,101 (0%) | 0% | 150.7 | 517,155 | Common Stock, $0.01 par value |
| Perry C. Siatis | EVP, GC AND SECRETARY | Exercise or conversion of derivative security received from the company (such as an option) at price $ 93.50 per share. | 21 Feb 2023 | 7,364 | 39,532 (0%) | 0% | 93.5 | 688,534 | Common Stock, $0.01 par value |
| Roxanne S. Austin | Director | Sale of securities on an exchange or to another person at price $ 150.50 per share. | 17 Feb 2023 | 6,222 | 34,483 (0%) | 0% | 150.5 | 936,411 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 149,732 | 652,985 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 34,937 | 687,922 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 39,022 | 726,944 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 33,210 | 760,154 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, CHAIRMAN OF THE BOARD AND CEO | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 114,787 | 114,787 | - | - | Option (Right to Buy) | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 7,380 | 93,089 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 21,944 | 21,944 | - | - | Option (Right to buy) | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 51,335 | 65,172 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 11,977 | 77,149 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 8,560 | 85,709 (0%) | 0% | 0 | Common stock, $0.01 par value | |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2023 | 25,000 | 0 | - | - | Option (Right to Buy) | |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 22,957 | 22,957 | - | - | Option (Right to Buy) | |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Sale of securities on an exchange or to another person at price $ 150.05 per share. | 16 Feb 2023 | 10,754 | 233,208 (0%) | 0% | 150.1 | 1,613,638 | Common Stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Sale of securities on an exchange or to another person at price $ 149.13 per share. | 16 Feb 2023 | 14,246 | 243,962 (0%) | 0% | 149.1 | 2,124,506 | Common Stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 51.42 per share. | 16 Feb 2023 | 25,000 | 258,208 (0%) | 0% | 51.4 | 1,285,500 | Common Stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 7,380 | 233,208 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 48,127 | 206,039 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 8,560 | 225,828 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Azita Saleki-Gerhardt | EVP, OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 11,229 | 217,268 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert A. Michael | VICE CHAIRMAN | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 45,577 | 45,577 | - | - | Option (Right to Buy) | |
| Robert A. Michael | VICE CHAIRMAN | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 13,218 | 136,832 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert A. Michael | VICE CHAIRMAN | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 69,517 | 107,394 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert A. Michael | VICE CHAIRMAN | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 10,148 | 146,980 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert A. Michael | VICE CHAIRMAN | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 16,220 | 123,614 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Brian L. Durkin | VP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 6,752 | 6,752 | - | - | Option (right to buy) | |
| Brian L. Durkin | VP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 16,042 | 35,136 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Brian L. Durkin | VP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 3,743 | 38,879 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Brian L. Durkin | VP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 2,306 | 44,331 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Brian L. Durkin | VP, CONTROLLER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 3,146 | 42,025 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Jeffrey Ryan Stewart | EVP, COMMERCIAL OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 7,486 | 100,512 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Jeffrey Ryan Stewart | EVP, COMMERCIAL OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 32,085 | 93,026 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Jeffrey Ryan Stewart | EVP, COMMERCIAL OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 35,111 | 35,111 | - | - | Option (Right to Buy) | |
| Jeffrey Ryan Stewart | EVP, COMMERCIAL OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 7,842 | 117,166 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Jeffrey Ryan Stewart | EVP, COMMERCIAL OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 8,812 | 109,324 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Thomas J. Hudson | SVP, R&D AND CSO | 16 Feb 2023 | 9,481 | 96,349 (0%) | 0% | 0 | Common Stock, $0.01 par value | ||
| Thomas J. Hudson | SVP, R&D AND CSO | 16 Feb 2023 | 5,350 | 109,251 (0%) | 0% | 0 | Common Stock, $0.01 par value | ||
| Thomas J. Hudson | SVP, R&D AND CSO | 16 Feb 2023 | 20,256 | 20,256 | - | - | Option (Right to Buy) | ||
| Thomas J. Hudson | SVP, R&D AND CSO | 16 Feb 2023 | 40,640 | 86,868 (0%) | 0% | 0 | Common Stock, $0.01 par value | ||
| Thomas J. Hudson | SVP, R&D AND CSO | 16 Feb 2023 | 7,552 | 103,901 (0%) | 0% | 0 | Common Stock, $0.01 par value | ||
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 3,146 | 27,036 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 33,760 | 33,760 | - | - | Option (Right to buy) | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 2,398 | 29,434 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 4,366 | 23,890 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Scott Reents | EVP, CHIEF FINANCIAL OFFICER | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 18,715 | 19,524 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2023 | 7,809 | 0 | - | - | Option (Right to Buy) | |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 6,546 | 47,209 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 5,074 | 52,283 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Exercise or conversion of derivative security received from the company (such as an option) at price $ 56.93 per share. | 16 Feb 2023 | 7,809 | 60,092 (0%) | 0% | 56.9 | 444,566 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Exercise or conversion of derivative security received from the company (such as an option) at price $ 67.25 per share. | 16 Feb 2023 | 6,370 | 66,462 (0%) | 0% | 67.3 | 428,383 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Sale of securities on an exchange or to another person at price $ 150.71 per share. | 16 Feb 2023 | 5,615 | 60,847 (0%) | 0% | 150.7 | 846,237 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Sale of securities on an exchange or to another person at price $ 151.28 per share. | 16 Feb 2023 | 7,780 | 53,067 (0%) | 0% | 151.3 | 1,176,958 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Sale of securities on an exchange or to another person at price $ 150.74 per share. | 16 Feb 2023 | 6,533 | 46,534 (0%) | 0% | 150.7 | 984,784 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Sale of securities on an exchange or to another person at price $ 151.29 per share. | 16 Feb 2023 | 7,646 | 38,888 (0%) | 0% | 151.3 | 1,156,763 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Sale of securities on an exchange or to another person at price $ 150.78 per share. | 16 Feb 2023 | 567 | 38,321 (0%) | 0% | 150.8 | 85,492 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Sale of securities on an exchange or to another person at price $ 151.34 per share. | 16 Feb 2023 | 400 | 37,921 (0%) | 0% | 151.3 | 60,536 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 16,205 | 16,205 | - | - | Option (Right to Buy) | |
| Carrie C. Strom | SVP & PRES GLOBAL ALLERG AESTH | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2023 | 6,370 | 0 | - | - | Option (Right to Buy) | |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Sale of securities on an exchange or to another person at price $ 151.29 per share. | 16 Feb 2023 | 8,420 | 62,679 (0%) | 0% | 151.3 | 1,273,862 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 Feb 2023 | 15,321 | 7,660 | - | - | Option (Right to Buy) | |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 4,658 | 58,805 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 3,874 | 62,679 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Exercise or conversion of derivative security received from the company (such as an option) at price $ 105.92 per share. | 16 Feb 2023 | 15,321 | 78,000 (0%) | 0% | 105.9 | 1,622,800 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Sale of securities on an exchange or to another person at price $ 150.74 per share. | 16 Feb 2023 | 6,901 | 71,099 (0%) | 0% | 150.7 | 1,040,257 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 13,166 | 13,166 | - | - | Option (Right to Buy) | |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 29,410 | 47,286 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Elaine K. Sorg | SVP, US COMMERCIAL OPERATIONS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 6,861 | 54,147 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 14,437 | 24,814 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 3,368 | 28,182 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 2,140 | 30,322 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 1,846 | 32,168 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Perry C. Siatis | EVP, GC AND SECRETARY | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Feb 2023 | 21,944 | 21,944 | - | - | Option (Right to buy) | |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2022 | 46 | 8,723 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Dec 2022 | 239 | 23,256 | - | - | Stock Equivalent Units | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 54.86 per share. | 12 Dec 2022 | 42,370 | 56,207 (0%) | 0% | 54.9 | 2,324,418 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 12 Dec 2022 | 42,370 | 0 | - | - | Option (Right to buy) | |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 164.10 per share. | 12 Dec 2022 | 3,075 | 13,837 (0%) | 0% | 164.1 | 504,608 | Common stock, $0.01 par value |
| Timothy J. Richmond | EVP, CHIEF HR OFFICER | Sale of securities on an exchange or to another person at price $ 163.39 per share. | 12 Dec 2022 | 39,295 | 16,912 (0%) | 0% | 163.4 | 6,420,410 | Common stock, $0.01 par value |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2022 | 55 | 8,598 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Sep 2022 | 288 | 22,806 | - | - | Stock Equivalent Units | |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2022 | 47 | 8,458 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 30 Jun 2022 | 237 | 22,296 | - | - | Stock Equivalent Units | |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 150.79 per share. | 23 May 2022 | 68,196 | 163,708 (0%) | 0% | 150.8 | 10,283,275 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 May 2022 | 21,739 | 43,478 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 May 2022 | 11,742 | 38,188 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 23 May 2022 | 46,320 | 0 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 151.53 per share. | 23 May 2022 | 11,605 | 152,103 (0%) | 0% | 151.5 | 1,758,506 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 105.92 per share. | 23 May 2022 | 21,739 | 231,904 (0%) | 0% | 105.9 | 2,302,595 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 93.50 per share. | 23 May 2022 | 11,742 | 210,165 (0%) | 0% | 93.5 | 1,097,877 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 114.36 per share. | 23 May 2022 | 46,320 | 198,423 (0%) | 0% | 114.4 | 5,297,155 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 154.80 per share. | 16 May 2022 | 53,327 | 152,503 (0%) | 0% | 154.8 | 8,255,020 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 May 2022 | 29,121 | 35,364 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 May 2022 | 70,879 | 0 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 155.27 per share. | 16 May 2022 | 2,100 | 152,103 (0%) | 0% | 155.3 | 326,067 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 154.49 per share. | 16 May 2022 | 54,279 | 154,203 (0%) | 0% | 154.5 | 8,385,563 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 153.43 per share. | 16 May 2022 | 43,621 | 208,482 (0%) | 0% | 153.4 | 6,692,770 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 93.50 per share. | 16 May 2022 | 64,636 | 252,103 (0%) | 0% | 93.5 | 6,043,466 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 79.02 per share. | 16 May 2022 | 35,364 | 187,467 (0%) | 0% | 79.0 | 2,794,463 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 79.02 per share. | 16 May 2022 | 29,121 | 252,103 (0%) | 0% | 79.0 | 2,301,141 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 155.44 per share. | 16 May 2022 | 400 | 152,103 (0%) | 0% | 155.4 | 62,176 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 154.04 per share. | 16 May 2022 | 46,273 | 205,830 (0%) | 0% | 154.0 | 7,127,893 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 61.36 per share. | 16 May 2022 | 70,879 | 222,982 (0%) | 0% | 61.4 | 4,349,135 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 May 2022 | 64,636 | 49,930 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 May 2022 | 35,364 | 0 | - | - | Option (Right to Buy) | |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 16 May 2022 | 83,960 | 0 | - | - | Option (Right to Buy) | |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 155.00 per share. | 16 May 2022 | 83,960 | 41,623 (0%) | 0% | 155 | 13,013,800 | Common Stock, $0.01 par value |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 54.86 per share. | 16 May 2022 | 83,960 | 125,583 (0%) | 0% | 54.9 | 4,606,046 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & Pres Global Allerg Aesth | Payment of exercise price or tax liability using portion of securities received from the company at price $ 152.09 per share. | 11 May 2022 | 2,876 | 40,663 (0%) | 0% | 152.1 | 437,411 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & Pres Global Allerg Aesth | Payment of exercise price or tax liability using portion of securities received from the company at price $ 152.83 per share. | 07 May 2022 | 234 | 43,539 (0%) | 0% | 152.8 | 35,762 | Common Stock, $0.01 par value |
| Frederick H. Waddell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2022 | 1,421 | 24,983 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Glenn F. Tilton | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2022 | 1,421 | 47,589 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Rebecca B. Roberts | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2022 | 1,421 | 9,753 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2022 | 1,421 | 31,542 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Thomas C. Freyman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2022 | 1,421 | 122,776 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2022 | 1,421 | 28,584 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Roxanne S. Austin | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2022 | 1,421 | 50,705 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Brett J. Hart | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2022 | 1,421 | 15,497 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| William H.L. Burnside | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2022 | 1,421 | 22,983 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 61.36 per share. | 06 May 2022 | 29,221 | 252,103 (0%) | 0% | 61.4 | 1,793,001 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 151.42 per share. | 06 May 2022 | 21,071 | 152,103 (0%) | 0% | 151.4 | 3,190,571 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 150.63 per share. | 06 May 2022 | 31,714 | 173,174 (0%) | 0% | 150.6 | 4,777,080 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 149.53 per share. | 06 May 2022 | 47,215 | 204,888 (0%) | 0% | 149.5 | 7,060,059 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.88 per share. | 06 May 2022 | 33,701 | 252,103 (0%) | 0% | 58.9 | 1,984,315 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 54.86 per share. | 06 May 2022 | 66,299 | 218,402 (0%) | 0% | 54.9 | 3,637,163 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 151.78 per share. | 06 May 2022 | 13,836 | 152,103 (0%) | 0% | 151.8 | 2,100,028 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 151.13 per share. | 06 May 2022 | 45,988 | 165,939 (0%) | 0% | 151.1 | 6,950,166 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 150.10 per share. | 06 May 2022 | 40,176 | 211,927 (0%) | 0% | 150.1 | 6,030,418 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 54.86 per share. | 06 May 2022 | 25,691 | 252,103 (0%) | 0% | 54.9 | 1,409,408 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 54.44 per share. | 06 May 2022 | 74,309 | 226,412 (0%) | 0% | 54.4 | 4,045,382 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.88 per share. | 06 May 2022 | 70,779 | 222,882 (0%) | 0% | 58.9 | 4,167,468 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 May 2022 | 29,221 | 70,879 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 May 2022 | 70,779 | 0 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 May 2022 | 33,701 | 70,779 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 May 2022 | 66,299 | 0 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 May 2022 | 25,691 | 66,299 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 06 May 2022 | 74,309 | 0 | - | - | Option (Right to Buy) | |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 152.83 per share. | 06 May 2022 | 48,591 | 152,103 (0%) | 0% | 152.8 | 7,426,163 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 152.24 per share. | 06 May 2022 | 28,536 | 200,694 (0%) | 0% | 152.2 | 4,344,321 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Sale of securities on an exchange or to another person at price $ 151.16 per share. | 06 May 2022 | 22,873 | 229,230 (0%) | 0% | 151.2 | 3,457,483 | Common Stock, $0.01 par value |
| Melody B. Meyer | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2022 | 1,421 | 12,523 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Edward M. Liddy | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2022 | 177 | 28,474 | - | - | Stock Equivalent Units | |
| Robert J. Alpern | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2022 | 44 | 8,335 | - | - | Stock Equivalent Units | |
| Edward J. Rapp | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 31 Mar 2022 | 217 | 21,860 | - | - | Stock Equivalent Units | |
| Jeffrey Ryan Stewart | EVP, Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 159.20 per share. | 24 Mar 2022 | 27,690 | 60,941 (0%) | 0% | 159.2 | 4,408,375 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 58.88 per share. | 24 Mar 2022 | 27,690 | 88,631 (0%) | 0% | 58.9 | 1,630,387 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, Chief Commercial Officer | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 24 Mar 2022 | 27,690 | 0 | - | - | Option (Right to Buy) | |
| Brian L. Durkin | VP, Controller | Sale of securities on an exchange or to another person at price $ 150.00 per share. | 09 Mar 2022 | 6,946 | 19,094 (0%) | 0% | 150.0 | 1,041,906 | Common Stock, $0.01 par value |
| Brian L. Durkin | VP, Controller | Exercise or conversion of derivative security received from the company (such as an option) at price $ 79.02 per share. | 09 Mar 2022 | 11,682 | 37,722 (0%) | 0% | 79.0 | 923,112 | Common Stock, $0.01 par value |
| Brian L. Durkin | VP, Controller | Sale of securities on an exchange or to another person at price $ 150.01 per share. | 09 Mar 2022 | 11,682 | 26,040 (0%) | 0% | 150.0 | 1,752,396 | Common Stock, $0.01 par value |
| Brian L. Durkin | VP, Controller | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 09 Mar 2022 | 11,682 | 0 | - | - | Option (Right to Buy) | |
| Carrie C. Strom | SVP & Pres Global Allerg Aesth | Payment of exercise price or tax liability using portion of securities received from the company at price $ 150.56 per share. | 05 Mar 2022 | 448 | 44,128 (0%) | 0% | 150.6 | 67,451 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & Pres Global Allerg Aesth | Payment of exercise price or tax liability using portion of securities received from the company at price $ 150.56 per share. | 05 Mar 2022 | 355 | 43,773 (0%) | 0% | 150.6 | 53,449 | Common Stock, $0.01 par value |
| Carrie C. Strom | SVP & Pres Global Allerg Aesth | Payment of exercise price or tax liability using portion of securities received from the company at price $ 147.69 per share. | 02 Mar 2022 | 810 | 44,576 (0%) | 0% | 147.7 | 119,629 | Common Stock, $0.01 par value |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 146.81 per share. | 01 Mar 2022 | 15,733 | 62,767 (0%) | 0% | 146.8 | 2,309,770 | Common Stock, $0.01 par value |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 147.60 per share. | 01 Mar 2022 | 5,167 | 57,600 (0%) | 0% | 147.6 | 762,657 | Common Stock, $0.01 par value |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 148.71 per share. | 01 Mar 2022 | 4,000 | 53,600 (0%) | 0% | 148.7 | 594,824 | Common Stock, $0.01 par value |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 149.38 per share. | 01 Mar 2022 | 100 | 53,500 (0%) | 0% | 149.4 | 14,938 | Common Stock, $0.01 par value |
| Laura J. Schumacher | Vice Chairman | Payment of exercise price or tax liability using portion of securities received from the company at price $ 149.54 per share. | 25 Feb 2022 | 40,490 | 248,002 (0%) | 0% | 149.5 | 6,054,875 | Common Stock, $0.01 par value |
| Richard A. Gonzalez | Director, Chairman of the Board and CEO | Gift of securities by or to the insider at price $ 0.00 per share. | 25 Feb 2022 | 2,610 | 606,065 (0%) | 0% | 0 | Common Stock, $0.01 par value | |
| Richard A. Gonzalez | Director, Chairman of the Board and CEO | Payment of exercise price or tax liability using portion of securities received from the company at price $ 149.54 per share. | 25 Feb 2022 | 102,812 | 503,253 (0%) | 0% | 149.5 | 15,374,506 | Common Stock, $0.01 par value |
| Timothy J. Richmond | EVP, Chief HR Officer | Sale of securities on an exchange or to another person at price $ 148.59 per share. | 25 Feb 2022 | 14,424 | 16,464 (0%) | 0% | 148.6 | 2,143,196 | Common Stock, $0.01 par value |
| Timothy J. Richmond | EVP, Chief HR Officer | Sale of securities on an exchange or to another person at price $ 147.52 per share. | 25 Feb 2022 | 9,381 | 30,888 (0%) | 0% | 147.5 | 1,383,918 | Common Stock, $0.01 par value |
| Timothy J. Richmond | EVP, Chief HR Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 149.54 per share. | 25 Feb 2022 | 21,027 | 40,269 (0%) | 0% | 149.5 | 3,144,378 | Common Stock, $0.01 par value |
| Timothy J. Richmond | EVP, Chief HR Officer | Sale of securities on an exchange or to another person at price $ 149.09 per share. | 25 Feb 2022 | 2,627 | 13,837 (0%) | 0% | 149.1 | 391,655 | Common Stock, $0.01 par value |
| Azita Saleki-Gerhardt | EVP, Operations | Payment of exercise price or tax liability using portion of securities received from the company at price $ 149.54 per share. | 25 Feb 2022 | 22,108 | 157,912 (0%) | 0% | 149.5 | 3,306,030 | Common Stock, $0.01 par value |
| Michael Severino | Vice Chairman | Payment of exercise price or tax liability using portion of securities received from the company at price $ 149.54 per share. | 25 Feb 2022 | 38,857 | 152,103 (0%) | 0% | 149.5 | 5,810,676 | Common Stock, $0.01 par value |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 149.14 per share. | 25 Feb 2022 | 1,101 | 41,623 (0%) | 0% | 149.1 | 164,208 | Common Stock, $0.01 par value |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 148.62 per share. | 25 Feb 2022 | 8,303 | 42,724 (0%) | 0% | 148.6 | 1,234,012 | Common Stock, $0.01 par value |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Sale of securities on an exchange or to another person at price $ 147.54 per share. | 25 Feb 2022 | 5,596 | 51,027 (0%) | 0% | 147.5 | 825,616 | Common Stock, $0.01 par value |
| Henry O. Gosebruch | EVP, Chief Strategy Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 149.54 per share. | 25 Feb 2022 | 30,156 | 56,623 (0%) | 0% | 149.5 | 4,509,528 | Common Stock, $0.01 par value |
| Robert A. Michael | Vice Chairman | Sale of securities on an exchange or to another person at price $ 149.06 per share. | 25 Feb 2022 | 4,236 | 37,877 (0%) | 0% | 149.1 | 631,432 | Common Stock, $0.01 par value |
| Robert A. Michael | Vice Chairman | Sale of securities on an exchange or to another person at price $ 148.49 per share. | 25 Feb 2022 | 26,937 | 42,113 (0%) | 0% | 148.5 | 3,999,878 | Common Stock, $0.01 par value |
| Robert A. Michael | Vice Chairman | Sale of securities on an exchange or to another person at price $ 147.41 per share. | 25 Feb 2022 | 11,932 | 69,050 (0%) | 0% | 147.4 | 1,758,937 | Common Stock, $0.01 par value |
| Robert A. Michael | Vice Chairman | Payment of exercise price or tax liability using portion of securities received from the company at price $ 149.54 per share. | 25 Feb 2022 | 34,286 | 80,982 (0%) | 0% | 149.5 | 5,127,128 | Common Stock, $0.01 par value |
| Brian L. Durkin | VP, Controller | Payment of exercise price or tax liability using portion of securities received from the company at price $ 149.54 per share. | 25 Feb 2022 | 7,589 | 26,040 (0%) | 0% | 149.5 | 1,134,859 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 149.04 per share. | 25 Feb 2022 | 2,600 | 60,941 (0%) | 0% | 149.0 | 387,493 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 148.49 per share. | 25 Feb 2022 | 12,659 | 63,541 (0%) | 0% | 148.5 | 1,879,779 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, Chief Commercial Officer | Sale of securities on an exchange or to another person at price $ 147.43 per share. | 25 Feb 2022 | 6,229 | 76,200 (0%) | 0% | 147.4 | 918,327 | Common Stock, $0.01 par value |
| Jeffrey Ryan Stewart | EVP, Chief Commercial Officer | Payment of exercise price or tax liability using portion of securities received from the company at price $ 149.54 per share. | 25 Feb 2022 | 17,093 | 82,429 (0%) | 0% | 149.5 | 2,556,087 | Common Stock, $0.01 par value |
| Thomas J. Hudson | SVP, R&D and CSO | 25 Feb 2022 | 13,408 | 46,228 (0%) | 0% | 149.5 | 2,005,032 | Common Stock, $0.01 par value | |
| Carrie C. Strom | SVP & Pres Global Allerg Aesth | Payment of exercise price or tax liability using portion of securities received from the company at price $ 149.54 per share. | 25 Feb 2022 | 2,840 | 45,386 (0%) | 0% | 149.5 | 424,694 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US Commercial Operations | Sale of securities on an exchange or to another person at price $ 148.59 per share. | 25 Feb 2022 | 3,451 | 18,576 (0%) | 0% | 148.6 | 512,783 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US Commercial Operations | Sale of securities on an exchange or to another person at price $ 149.07 per share. | 25 Feb 2022 | 700 | 17,876 (0%) | 0% | 149.1 | 104,351 | Common Stock, $0.01 par value |
| Elaine K. Sorg | SVP, US Commercial Operations | Sale of securities on an exchange or to another person at price $ 147.59 per share. | 25 Feb 2022 | 2,333 | 22,027 (0%) | 0% | 147.6 | 344,333 | Common Stock, $0.01 par value |